Diagnosis of Premature Rupture of Foetal Membranes

نویسنده

  • Leena Rahkonen
چکیده

Premature rupture of foetal membranes (PROM) complicates 10 % of pregnancies and is the most important identifiable cause of pre-term delivery. The diagnosis of PROM is based on the detection of amniotic fluid in the vagina. This can be achieved by chemical, clinical or biochemical methods. An ideal test should be specific for amniotic fluid and should not be affected by gestational age or interfering factors present in vaginal samples. Several studies have demonstrated that the rapid test based on insulin-like growth factor-binding protein-1 (IGFBP-1) fulfils these requirements, making it an ideal tool for PROM diagnosis.

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تاریخ انتشار 2012